Grifolic armour is a medium level degradable magical armour in RuneScape which requires 60 Magic and Defence and degrades over 10 hours once used. The visor, poncho, and leggings are created by using the Crafting ability to connect grifolic flakes to a piece of mycelium web armour using a needle and thread.

The other items do not degrade and are obtainable as monster drops. The orb and gloves are dropped by grifolaroos, while the wand and shield are dropped by grifolapines.

The armour is not typically used because it is expensive to keep up compared to other armours because of the material cost of every repair and the high skill. Additionally, the level which is required to wear the armour is quite low and easily outtrained and replaced by higher level armour. Batwing armour is usually preferable, because it provides roughly similar life point and defence bonuses and is considerably cheaper.